Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agents

BACKGROUND: Ischemia of the bile duct is a common feature in liver disease and transplantation, which represents a major cause of morbidity and mortality, especially after liver transplantation. Detailed knowledge of its pathogenesis remains incomplete due to the lack of appropriate in vitro models....

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Detalles Bibliográficos
Autores principales: Shi, Shaojun, Roest, Henk P., van den Bosch, Thierry P.P., Bijvelds, Marcel J.C., Boehnert, Markus U., de Jonge, Jeroen, Dekker, Sven O., de Vries, Antoine A.F., de Jonge, Hugo R., Verstegen, Monique M.A., van der Laan, Luc J.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826934/
https://www.ncbi.nlm.nih.gov/pubmed/36608526
http://dx.doi.org/10.1016/j.ebiom.2022.104431

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