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Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats

BACKGROUND: In the last decades different preclinical animal models of Parkinson's disease (PD) have been generated, aiming to mimic the progressive neuronal loss of midbrain dopaminergic (DA) cells as well as motor and non-motor impairment. Among all the available models, AAV-based models of h...

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Detalles Bibliográficos
Autores principales:	Gubinelli, F., Sarauskyte, L., Venuti, C., Kulacz, I., Cazzolla, G., Negrini, M., Anwer, D., Vecchio, I., Jakobs, F., Manfredsson, F.P., Davidsson, M., Heuer, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827042/ https://www.ncbi.nlm.nih.gov/pubmed/36632447 http://dx.doi.org/10.1016/j.crneur.2022.100065

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