DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice

OBJECTIVES: The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth and metabolism. In mice, activation of mTOR controls cold adaptation by promoting the recruitment and the activation of brown adipose tissue (BAT). DEP-domain containing mTOR-interacting protein...

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Detalles Bibliográficos
Autores principales: Colas, Charles, Mouchiroud, Mathilde, Al Dow, Manal, Kolnohuz, Alona, Gélinas, Yves, Caron, Alexandre, Laplante, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827061/
https://www.ncbi.nlm.nih.gov/pubmed/36535626
http://dx.doi.org/10.1016/j.molmet.2022.101660

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