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RHOA-regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia

The Philadelphia 9;22 chromosome translocation has two common isoforms that are preferentially associated with distinct subtypes of leukemia. The p210 variant is the hallmark of chronic myeloid leukemia (CML) whereas p190 is frequently associated with B-cell acute lymphoblastic leukemia. The only se...

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Detalles Bibliográficos
Autores principales: Zhang, Hualei, Cai, Baohuan, Liu, Yun, Chong, Yating, Matsunaga, Atsuko, Mori, Stephanie Fay, Fang, Xuexiu, Kitamura, Eiko, Chang, Chang-Sheng, Wang, Ping, Cowell, John K., Hu, Tianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827165/
https://www.ncbi.nlm.nih.gov/pubmed/35833297
http://dx.doi.org/10.3324/haematol.2022.280757