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Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey

BACKGROUND AND AIMS: Androgenic‐anabolic steroid (AAS) abuse is a global health concern, studies revealing an increasing trend of abuse and deleterious effects on reproductive health. Unfortunately, there is no consensus about management pathways due to the lack of specific guidelines. METHODS: A pr...

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Autores principales: Al Hashimi, Manaf, Farahat, Yasser, Kandil, Hussein, Al Khalidi, Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827233/
https://www.ncbi.nlm.nih.gov/pubmed/36628108
http://dx.doi.org/10.1002/hsr2.1032
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author Al Hashimi, Manaf
Farahat, Yasser
Kandil, Hussein
Al Khalidi, Ismail
author_facet Al Hashimi, Manaf
Farahat, Yasser
Kandil, Hussein
Al Khalidi, Ismail
author_sort Al Hashimi, Manaf
collection PubMed
description BACKGROUND AND AIMS: Androgenic‐anabolic steroid (AAS) abuse is a global health concern, studies revealing an increasing trend of abuse and deleterious effects on reproductive health. Unfortunately, there is no consensus about management pathways due to the lack of specific guidelines. METHODS: A prospective study, multicentre, online survey, composed of 30 questions, was conducted to investigate the current trend of AAS abuse and the management followed by practitioners from different specialities dealing with this condition. RESULTS: A total of 151 respondents were included. The majority were general urologists (68.21%), andrologists (22.51%), and endocrinologists (9.28%). An increasing trend of AAS abuse was noticed by 90.73% of participants mostly in young age populations. Most of AAS abusers were presented with infertility (64.24%) and erectile dysfunction (59.60%), and their investigations showed abnormal semen analysis (77.48%), abnormal hormones (follicle‐stimulating hormone, luteinizing hormone, testosterone, and estradiol) (94.70%), and reduction in testicular size (50.33%). Most of respondents expected: the need of long duration for spontaneous recovery (6–12 months), relapse of AAS abuse in one‐third of patients, less knowledge about the adverse effects (39.74%), and risk of drug dependence (54.30%). Immediate treatment was the most offered plan of management (44.37%) followed by a waiting spontaneous recovery (32.45%), while the remaining would refer the patients to an either endocrinologist or andrologist. The treating physicians did not follow specific guidelines and most of participants (44.44%) reverted to their personal experience in the management. CONCLUSIONS: Our study revealed an increasing trend of AAS abuse, deleterious effects of AAS use on reproductive health, and lack of consensuses among the treating physicians regarding the management of related adverse effects. Our study could be considered a call to the scientific bodies to have more studies, establish guidelines for management, and to have better awareness of this serious public health concern.
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spelling pubmed-98272332023-01-09 Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey Al Hashimi, Manaf Farahat, Yasser Kandil, Hussein Al Khalidi, Ismail Health Sci Rep Original Research BACKGROUND AND AIMS: Androgenic‐anabolic steroid (AAS) abuse is a global health concern, studies revealing an increasing trend of abuse and deleterious effects on reproductive health. Unfortunately, there is no consensus about management pathways due to the lack of specific guidelines. METHODS: A prospective study, multicentre, online survey, composed of 30 questions, was conducted to investigate the current trend of AAS abuse and the management followed by practitioners from different specialities dealing with this condition. RESULTS: A total of 151 respondents were included. The majority were general urologists (68.21%), andrologists (22.51%), and endocrinologists (9.28%). An increasing trend of AAS abuse was noticed by 90.73% of participants mostly in young age populations. Most of AAS abusers were presented with infertility (64.24%) and erectile dysfunction (59.60%), and their investigations showed abnormal semen analysis (77.48%), abnormal hormones (follicle‐stimulating hormone, luteinizing hormone, testosterone, and estradiol) (94.70%), and reduction in testicular size (50.33%). Most of respondents expected: the need of long duration for spontaneous recovery (6–12 months), relapse of AAS abuse in one‐third of patients, less knowledge about the adverse effects (39.74%), and risk of drug dependence (54.30%). Immediate treatment was the most offered plan of management (44.37%) followed by a waiting spontaneous recovery (32.45%), while the remaining would refer the patients to an either endocrinologist or andrologist. The treating physicians did not follow specific guidelines and most of participants (44.44%) reverted to their personal experience in the management. CONCLUSIONS: Our study revealed an increasing trend of AAS abuse, deleterious effects of AAS use on reproductive health, and lack of consensuses among the treating physicians regarding the management of related adverse effects. Our study could be considered a call to the scientific bodies to have more studies, establish guidelines for management, and to have better awareness of this serious public health concern. John Wiley and Sons Inc. 2023-01-09 /pmc/articles/PMC9827233/ /pubmed/36628108 http://dx.doi.org/10.1002/hsr2.1032 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Al Hashimi, Manaf
Farahat, Yasser
Kandil, Hussein
Al Khalidi, Ismail
Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title_full Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title_fullStr Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title_full_unstemmed Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title_short Androgenic‐anabolic steroid abuse trend and management: A prospective, cross‐sectional, questionnaire‐based survey
title_sort androgenic‐anabolic steroid abuse trend and management: a prospective, cross‐sectional, questionnaire‐based survey
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827233/
https://www.ncbi.nlm.nih.gov/pubmed/36628108
http://dx.doi.org/10.1002/hsr2.1032
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