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S100A1 expression is increased in spinal cord injury and promotes inflammation, oxidative stress and apoptosis of PC12 cells induced by LPS via ERK signaling

Spinal cord injury (SCI) is a severe neurological disorder and the molecular mechanisms leading to its poor prognosis remain to be elucidated. S100A1, a mediator of Ca(2+) handling of sarcoplasmic reticulum and mitochondrial function, operates as an endogenous danger signal (alarmin) associated with...

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Detalles Bibliográficos
Autores principales: Bai, Ye, Guo, Ning, Xu, Zhanwu, Chen, Yuxi, Zhang, Wenjin, Chen, Qinghe, Bi, Zhenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827259/
https://www.ncbi.nlm.nih.gov/pubmed/36524376
http://dx.doi.org/10.3892/mmr.2022.12917

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