Cargando…

Downregulation of ITIH3 contributes to cisplatin-based chemotherapy resistance in ovarian carcinoma via the Bcl-2 mediated anti-apoptosis signaling pathway

Platinum resistance of ovarian cancer is one of the primary factors of poor prognosis and inter-α-trypsin inhibitor heavy chain 3 (ITIH3) is a potential DDP resistance-associated gene. The present study assessed protein expression levels of ITIH3 in human ovarian cancer and evaluated the relationshi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yingzhao, Shi, Lijun, Yuan, Cunzhong, Feng, Yan, Li, Mengdi, Liu, Hongmei, Chen, Xi, Yao, Desheng, Wang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827458/ https://www.ncbi.nlm.nih.gov/pubmed/36644154 http://dx.doi.org/10.3892/ol.2022.13646

Ejemplares similares

ITIH5, a p53-responsive gene, inhibits the growth and metastasis of melanoma cells by downregulating the transcriptional activity of KLF4
por: Liu, Jia, et al.
Publicado: (2021)

ITIH5 mediates epigenetic reprogramming of breast cancer cells
por: Rose, Michael, et al.
Publicado: (2017)

Suppression of pancreatic cancer liver metastasis by secretion-deficient ITIH5
por: Young, Eric D., et al.
Publicado: (2020)

BNIP3 contributes to cisplatin‐induced apoptosis in ovarian cancer cells
por: Jia, Jinghui, et al.
Publicado: (2020)

ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism
por: Pihl, Rasmus, et al.
Publicado: (2021)

Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51
por: Wang, Bingliang, et al.
Publicado: (2015)

Downregulation of hTERT contributes to ovarian cancer apoptosis and inhibits proliferation of ovarian cancer cells
por: Wang, Qing-An-Zi, et al.
Publicado: (2020)

Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia
por: Oing, Christoph, et al.
Publicado: (2011)

Integrative analyses indicate an association between ITIH3 polymorphisms with autism spectrum disorder
por: Xie, Xinyan, et al.
Publicado: (2020)

Downregulation of LINC01508 contributes to cisplatin resistance in ovarian cancer via the regulation of the Hippo-YAP pathway
por: Xiao, Lan, et al.
Publicado: (2021)

Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation
por: Roy, H K, et al.
Publicado: (2001)

Small-molecule inhibitor of Bcl-2 (TW-37) suppresses growth and enhances cisplatin-induced apoptosis in ovarian cancer cells
por: Wang, Haixia, et al.
Publicado: (2015)

Pan-cancer analysis identifies ITIH1 as a novel prognostic indicator for hepatocellular carcinoma
por: Chang, Qing-hua, et al.
Publicado: (2021)

BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin
por: Bansal, Nisha, et al.
Publicado: (2012)

Effects of Helicobacter pylori infection and interleukin 6 on the expression of ITIH4 in human gastric cancer cells
por: Jing, Dadao, et al.
Publicado: (2020)

ITIH5-Derived Polypeptides Covering the VIT Domain Suppress the Growth of Human Cancer Cells In Vitro
por: Rose, Michael, et al.
Publicado: (2022)

BCL2A1 and CCL18 Are Predictive Biomarkers of Cisplatin Chemotherapy and Immunotherapy in Colon Cancer Patients
por: Yue, Taohua, et al.
Publicado: (2022)

CUEDC2 Contributes to Cisplatin-Based Chemotherapy Resistance in Ovarian Serious Carcinoma by Regulating p38 MAPK Signaling
por: Wang, Aichun, et al.
Publicado: (2019)

Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2
por: LI, LIN, et al.
Publicado: (2016)

Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2
por: Li, Lin, et al.
Publicado: (2019)

Intraoperative intraperitoneal chemotherapy with cisplatin in epithelial ovarian cancer
por: Kim, Myung Joo, et al.
Publicado: (2012)

Dicer affects cisplatin-mediated apoptosis in epithelial ovarian cancer cells
por: Wang, Xi, et al.
Publicado: (2018)

Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells
por: Liu, Li, et al.
Publicado: (2019)

Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression
por: Li, Yifan, et al.
Publicado: (2022)

Long Non-coding RNA ITIH4-AS1 Accelerates the Proliferation and Metastasis of Colorectal Cancer by Activating JAK/STAT3 Signaling
por: Liang, Chaojie, et al.
Publicado: (2019)

Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer
por: Zhang, Xiaoyi, et al.
Publicado: (2022)

Hyperthermic intrathoracic chemotherapy with cisplatin for ovarian cancer with pleural metastasis
por: Jun, Su Youn, et al.
Publicado: (2017)

MicroRNA-377 Downregulates Bcl-xL and Increases Apoptosis in Hepatocellular Carcinoma Cells
por: Ge, Hongyan, et al.
Publicado: (2017)

Isoalantolactone Suppresses Glycolysis and Resensitizes Cisplatin-Based Chemotherapy in Cisplatin-Resistant Ovarian Cancer Cells
por: Chun, Jaemoo
Publicado: (2023)

ITIH4: A New Potential Biomarker of “Toxin Syndrome” in Coronary Heart Disease Patient Identified with Proteomic Method
por: Xu, Hao, et al.
Publicado: (2013)

Long noncoding RNA LINC00261 upregulates ITIH5 to impair tumorigenic ability of pancreatic cancer stem cells
por: Zou, Lijuan, et al.
Publicado: (2021)

Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4 (ITIH4) in Autoimmune Cholestatic Liver Diseases
por: Laursen, Tea Lund, et al.
Publicado: (2022)

Piperidine nitroxide Tempol enhances cisplatin-induced apoptosis in ovarian cancer cells
por: Wang, Meng, et al.
Publicado: (2018)

Apoptosis is augmented in high-grade serous ovarian cancer by the combined inhibition of Bcl-2/Bcl-xL and PARP
por: Yokoyama, Takuhei, et al.
Publicado: (2017)

Real-time assessment of platinum sensitivity of primary culture from a patient with ovarian cancer with extensive metastasis and the platinum sensitivity enhancing effect by metformin
por: Liu, Yingzhao, et al.
Publicado: (2018)

Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis
por: Lin, Xiaojie, et al.
Publicado: (2014)

miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells
por: Shi, Xiaoyan, et al.
Publicado: (2018)

MiR‐335‐5p restores cisplatin sensitivity in ovarian cancer cells through targeting BCL2L2
por: Liu, Ruonan, et al.
Publicado: (2018)

The involvement of Bcl-2 family proteins in AKT-regulated cell survival in cisplatin resistant epithelial ovarian cancer
por: Dai, Yan, et al.
Publicado: (2016)

3065 A1BG and ITIH4 proteins are upregulated on HDL of youth with type 1 diabetes and correlate with glycemic control
por: Gourgari, Evgenia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lq74o2aoribq7553ejlglmtdgl