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Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochez...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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D.A. Spandidos
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827464/ https://www.ncbi.nlm.nih.gov/pubmed/36644135 http://dx.doi.org/10.3892/ol.2022.13643 |
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author | Liu, Lei Chen, Shiqiang Wang, Lihua |
author_facet | Liu, Lei Chen, Shiqiang Wang, Lihua |
author_sort | Liu, Lei |
collection | PubMed |
description | Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochezia and multiple retroperitoneal masses were found through computed tomography (CT). Histopathological examination showed that the tumor was mainly comprised of short spindle cells, arranged into sparse and dense areas. Mitotic figures were observed, generally 6–8 mitoses/10 high power fields, along with local necrosis. The tumor invaded the circumferential liver, intestines, lymphatic vessels and lymph nodes. Combined with the immunohistochemical results, it was diagnosed as a malignant SFT, which regrew just 2 months after the latest surgery. Retroperitoneal SFTs with repeated relapses, infiltrative growth and lymphatic metastasis suggest the need for careful and long-term follow-up. |
format | Online Article Text |
id | pubmed-9827464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-98274642023-01-13 Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report Liu, Lei Chen, Shiqiang Wang, Lihua Oncol Lett Articles Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochezia and multiple retroperitoneal masses were found through computed tomography (CT). Histopathological examination showed that the tumor was mainly comprised of short spindle cells, arranged into sparse and dense areas. Mitotic figures were observed, generally 6–8 mitoses/10 high power fields, along with local necrosis. The tumor invaded the circumferential liver, intestines, lymphatic vessels and lymph nodes. Combined with the immunohistochemical results, it was diagnosed as a malignant SFT, which regrew just 2 months after the latest surgery. Retroperitoneal SFTs with repeated relapses, infiltrative growth and lymphatic metastasis suggest the need for careful and long-term follow-up. D.A. Spandidos 2022-12-20 /pmc/articles/PMC9827464/ /pubmed/36644135 http://dx.doi.org/10.3892/ol.2022.13643 Text en Copyright: © Liu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Liu, Lei Chen, Shiqiang Wang, Lihua Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title | Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title_full | Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title_fullStr | Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title_full_unstemmed | Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title_short | Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report |
title_sort | retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827464/ https://www.ncbi.nlm.nih.gov/pubmed/36644135 http://dx.doi.org/10.3892/ol.2022.13643 |
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