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Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report

Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochez...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Chen, Shiqiang, Wang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827464/
https://www.ncbi.nlm.nih.gov/pubmed/36644135
http://dx.doi.org/10.3892/ol.2022.13643
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author Liu, Lei
Chen, Shiqiang
Wang, Lihua
author_facet Liu, Lei
Chen, Shiqiang
Wang, Lihua
author_sort Liu, Lei
collection PubMed
description Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochezia and multiple retroperitoneal masses were found through computed tomography (CT). Histopathological examination showed that the tumor was mainly comprised of short spindle cells, arranged into sparse and dense areas. Mitotic figures were observed, generally 6–8 mitoses/10 high power fields, along with local necrosis. The tumor invaded the circumferential liver, intestines, lymphatic vessels and lymph nodes. Combined with the immunohistochemical results, it was diagnosed as a malignant SFT, which regrew just 2 months after the latest surgery. Retroperitoneal SFTs with repeated relapses, infiltrative growth and lymphatic metastasis suggest the need for careful and long-term follow-up.
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spelling pubmed-98274642023-01-13 Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report Liu, Lei Chen, Shiqiang Wang, Lihua Oncol Lett Articles Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67-year-old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochezia and multiple retroperitoneal masses were found through computed tomography (CT). Histopathological examination showed that the tumor was mainly comprised of short spindle cells, arranged into sparse and dense areas. Mitotic figures were observed, generally 6–8 mitoses/10 high power fields, along with local necrosis. The tumor invaded the circumferential liver, intestines, lymphatic vessels and lymph nodes. Combined with the immunohistochemical results, it was diagnosed as a malignant SFT, which regrew just 2 months after the latest surgery. Retroperitoneal SFTs with repeated relapses, infiltrative growth and lymphatic metastasis suggest the need for careful and long-term follow-up. D.A. Spandidos 2022-12-20 /pmc/articles/PMC9827464/ /pubmed/36644135 http://dx.doi.org/10.3892/ol.2022.13643 Text en Copyright: © Liu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Liu, Lei
Chen, Shiqiang
Wang, Lihua
Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title_full Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title_fullStr Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title_full_unstemmed Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title_short Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
title_sort retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827464/
https://www.ncbi.nlm.nih.gov/pubmed/36644135
http://dx.doi.org/10.3892/ol.2022.13643
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