Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD

Obliterating skeletal muscle Orai1 expression improves muscle pathology in the mdx mouse model of DMD—could Orai1 emerge as a potential drug target?

Detalles Bibliográficos
Autores principales: Cheng, Arthur J., von Walden, Ferdinand, Lanner, Johanna T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827522/
https://www.ncbi.nlm.nih.gov/pubmed/36595663
http://dx.doi.org/10.1085/jgp.202213224
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author Cheng, Arthur J.
von Walden, Ferdinand
Lanner, Johanna T.
author_facet Cheng, Arthur J.
von Walden, Ferdinand
Lanner, Johanna T.
author_sort Cheng, Arthur J.
collection PubMed
description Obliterating skeletal muscle Orai1 expression improves muscle pathology in the mdx mouse model of DMD—could Orai1 emerge as a potential drug target?
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spelling pubmed-98275222023-07-03 Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD Cheng, Arthur J. von Walden, Ferdinand Lanner, Johanna T. J Gen Physiol Commentary Obliterating skeletal muscle Orai1 expression improves muscle pathology in the mdx mouse model of DMD—could Orai1 emerge as a potential drug target? Rockefeller University Press 2023-01-03 /pmc/articles/PMC9827522/ /pubmed/36595663 http://dx.doi.org/10.1085/jgp.202213224 Text en © 2023 Cheng et al. https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Cheng, Arthur J.
von Walden, Ferdinand
Lanner, Johanna T.
Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title_full Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title_fullStr Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title_full_unstemmed Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title_short Orai1 as a potential “fits-all approach” therapeutic target for the treatment of DMD
title_sort orai1 as a potential “fits-all approach” therapeutic target for the treatment of dmd
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827522/
https://www.ncbi.nlm.nih.gov/pubmed/36595663
http://dx.doi.org/10.1085/jgp.202213224
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