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Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma

BACKGROUND: This study aimed to validate whether infusion of GD2-specific fourth-generation safety-designed chimeric antigen receptor (4SCAR)-T cells is safe and whether CAR-T cells exert anti-glioblastoma (GBM) activity. METHODS: A total of eight patients with GD2-positive GBM were enrolled and inf...

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Detalles Bibliográficos
Autores principales:	Liu, Zhuohao, Zhou, Jiayi, Yang, Xinzhi, Liu, Yuchen, Zou, Chang, Lv, Wen, Chen, Cheng, Cheng, Kenneth King-yip, Chen, Tao, Chang, Lung-Ji, Wu, Dinglan, Mao, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827625/ https://www.ncbi.nlm.nih.gov/pubmed/36617554 http://dx.doi.org/10.1186/s12943-022-01711-9

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