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p85S6K sustains synaptic GluA1 to ameliorate cognitive deficits in Alzheimer’s disease

BACKGROUND: Ribosomal protein S6 kinase 1 (S6K1) is a serine–threonine kinase that has two main isoforms: p70S6K (70-kDa isoform) and p85S6K (85-kDa isoform). p70S6K, with its upstream mammalian target of rapamycin (mTOR), has been shown to be involved in learning and memory and participate in the p...

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Detalles Bibliográficos
Autores principales:	Li, Jia-Bing, Hu, Xiao-Yu, Chen, Mu-Wen, Xiong, Cai-Hong, Zhao, Na, Ge, Yan-Hui, Wang, Hao, Gao, Xiao-Ling, Xu, Nan-Jie, Zhao, Lan-Xue, Yu, Zhi-Hua, Chen, Hong-Zhuan, Qiu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827685/ https://www.ncbi.nlm.nih.gov/pubmed/36624510 http://dx.doi.org/10.1186/s40035-022-00334-w

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