Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration

BACKGROUND: Schwann cells (SCs) respond to nerve injury by transforming into the repair-related cell phenotype, which can provide the essential signals and spatial cues to promote axonal regeneration and induce target reinnervation. Endothelial cells (ECs) contribute to intraneural angiogenesis cont...

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Detalles Bibliográficos
Autores principales: Huang, Jinsheng, Zhang, Geyi, Li, Senrui, Li, Jiangnan, Wang, Wengang, Xue, Jiajia, Wang, Yuanyi, Fang, Mengyuan, Zhou, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827708/
https://www.ncbi.nlm.nih.gov/pubmed/36624511
http://dx.doi.org/10.1186/s12951-023-01767-9

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