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An improved cell line-derived xenograft humanized mouse model for evaluation of PD-1/PD-L1 blocker BMS202-induced immune responses in colorectal cancer: An improved humanized mouse model for the evaluation of immunotherapy

The establishment of an in vivo mouse model mimicking human tumor-immune environments provides a promising platform for immunotherapy assessment, drug discovery and clinical decision guidance. To this end, we construct humanized NCG mice by transplanting human hCD34 (+) hematopoietic progenitors int...

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Detalles Bibliográficos
Autores principales:	Shang, Pengzhao, Yu, Liting, Cao, Shucheng, Guo, Changying, Zhang, Wanheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827804/ https://www.ncbi.nlm.nih.gov/pubmed/36269133 http://dx.doi.org/10.3724/abbs.2022145

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