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AID function in somatic hypermutation and class switch recombination: AID function in somatic hypermutation and class switch recombination

Activation-induced cytidine deaminase (AID) initiates somatic hypermutation of immunoglobulin (Ig) gene variable regions and class switch recombination (CSR) of Ig heavy chain constant regions. Two decades of intensive research has greatly expanded our knowledge of how AID functions in peripheral B...

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Detalles Bibliográficos
Autor principal: Yu, Kefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827813/
https://www.ncbi.nlm.nih.gov/pubmed/35975606
http://dx.doi.org/10.3724/abbs.2022070