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AID function in somatic hypermutation and class switch recombination: AID function in somatic hypermutation and class switch recombination
Activation-induced cytidine deaminase (AID) initiates somatic hypermutation of immunoglobulin (Ig) gene variable regions and class switch recombination (CSR) of Ig heavy chain constant regions. Two decades of intensive research has greatly expanded our knowledge of how AID functions in peripheral B...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827813/ https://www.ncbi.nlm.nih.gov/pubmed/35975606 http://dx.doi.org/10.3724/abbs.2022070 |