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Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial
OBJECTIVE: To assess the 6‐month outcome and survival of enhanced polyethylene terephthalate (PET) implants as a replacement for the cranial cruciate ligament (CCL) in dogs with spontaneous CCL disease (CCLD). STUDY DESIGN: Pilot, prospective case series. ANIMALS: Ten client‐owned large breed dogs w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827950/ https://www.ncbi.nlm.nih.gov/pubmed/36165283 http://dx.doi.org/10.1111/vsu.13889 |
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author | Johnson, Tiffany A. Conzemius, Michael G. |
author_facet | Johnson, Tiffany A. Conzemius, Michael G. |
author_sort | Johnson, Tiffany A. |
collection | PubMed |
description | OBJECTIVE: To assess the 6‐month outcome and survival of enhanced polyethylene terephthalate (PET) implants as a replacement for the cranial cruciate ligament (CCL) in dogs with spontaneous CCL disease (CCLD). STUDY DESIGN: Pilot, prospective case series. ANIMALS: Ten client‐owned large breed dogs with unilateral spontaneous CCLD. METHODS: Dogs were evaluated before and 6 months after intra‐articular placement of a PET implant with the Liverpool Osteoarthritis in Dogs questionnaire and force platform gait analysis. Arthroscopy was performed 6 months after surgery to visually assess implant integrity. RESULTS: Scores on owner questionnaires and limb asymmetry improved in all dogs that reached the 6‐month time point, by 51.7% (p = .008) and 86% (p = .002), respectively. The PET implant appeared intact and functioning in two stifles, partially intact and functioning in four stifles and completely torn in three stifles. One dog had an implant infection and was removed from the study. Evidence of deterioration and tearing occurred in the midbody of the implant. CONCLUSION: Although function improved over the course of this study, only 2/10 implants appeared intact 6 months after placement. CLINICAL SIGNIFICANCE: Implant survivability prohibits further clinical investigation using this implant. |
format | Online Article Text |
id | pubmed-9827950 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98279502023-01-10 Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial Johnson, Tiffany A. Conzemius, Michael G. Vet Surg Clinical Research OBJECTIVE: To assess the 6‐month outcome and survival of enhanced polyethylene terephthalate (PET) implants as a replacement for the cranial cruciate ligament (CCL) in dogs with spontaneous CCL disease (CCLD). STUDY DESIGN: Pilot, prospective case series. ANIMALS: Ten client‐owned large breed dogs with unilateral spontaneous CCLD. METHODS: Dogs were evaluated before and 6 months after intra‐articular placement of a PET implant with the Liverpool Osteoarthritis in Dogs questionnaire and force platform gait analysis. Arthroscopy was performed 6 months after surgery to visually assess implant integrity. RESULTS: Scores on owner questionnaires and limb asymmetry improved in all dogs that reached the 6‐month time point, by 51.7% (p = .008) and 86% (p = .002), respectively. The PET implant appeared intact and functioning in two stifles, partially intact and functioning in four stifles and completely torn in three stifles. One dog had an implant infection and was removed from the study. Evidence of deterioration and tearing occurred in the midbody of the implant. CONCLUSION: Although function improved over the course of this study, only 2/10 implants appeared intact 6 months after placement. CLINICAL SIGNIFICANCE: Implant survivability prohibits further clinical investigation using this implant. John Wiley & Sons, Inc. 2022-09-27 2022-11 /pmc/articles/PMC9827950/ /pubmed/36165283 http://dx.doi.org/10.1111/vsu.13889 Text en © 2022 The Authors. Veterinary Surgery published by Wiley Periodicals LLC on behalf of American College of Veterinary Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Clinical Research Johnson, Tiffany A. Conzemius, Michael G. Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title | Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title_full | Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title_fullStr | Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title_full_unstemmed | Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title_short | Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial |
title_sort | outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: a pilot clinical trial |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827950/ https://www.ncbi.nlm.nih.gov/pubmed/36165283 http://dx.doi.org/10.1111/vsu.13889 |
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