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Computational investigations on target-site searching and recognition mechanisms by thymine DNA glycosylase during DNA repair process: Structural dynamics of TDG at atomic resolution
DNA glycosylase, as one member of DNA repair machineries, plays an essential role in correcting mismatched/damaged DNA nucleotides by cleaving the N-glycosidic bond between the sugar and target nucleobase through the base excision repair (BER) pathways. Efficient corrections of these DNA lesions are...
Autores principales: | Wang, Lingyan, Song, Kaiyuan, Yu, Jin, Da, Lin-Tai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828053/ https://www.ncbi.nlm.nih.gov/pubmed/35593467 http://dx.doi.org/10.3724/abbs.2022050 |
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