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Computational investigations on target-site searching and recognition mechanisms by thymine DNA glycosylase during DNA repair process: Structural dynamics of TDG at atomic resolution

DNA glycosylase, as one member of DNA repair machineries, plays an essential role in correcting mismatched/damaged DNA nucleotides by cleaving the N-glycosidic bond between the sugar and target nucleobase through the base excision repair (BER) pathways. Efficient corrections of these DNA lesions are...

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Detalles Bibliográficos
Autores principales: Wang, Lingyan, Song, Kaiyuan, Yu, Jin, Da, Lin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828053/
https://www.ncbi.nlm.nih.gov/pubmed/35593467
http://dx.doi.org/10.3724/abbs.2022050

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