KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H (2)S axis and contributes to pancreatic cancer growth : Nrf2/CSE/H (2)S axis decreases ROS in pancreatic cancer

In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor. However, the regulation of intracellular ROS levels in KRAS mutant pancre...

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Detalles Bibliográficos
Autores principales: Fan, Kun, Zhang, Shulong, Ni, Xiaojian, Shen, Sheng, Wang, Jiwen, Sun, Wentao, Suo, Tao, Liu, Han, Ni, Xiaoling, Liu, Houbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828102/
https://www.ncbi.nlm.nih.gov/pubmed/36514219
http://dx.doi.org/10.3724/abbs.2022173

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