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Ultrahigh‐Throughput Screening of an Artificial Metalloenzyme using Double Emulsions
The potential for ultrahigh‐throughput compartmentalization renders droplet microfluidics an attractive tool for the directed evolution of enzymes. Importantly, it ensures maintenance of the phenotype‐genotype linkage, enabling reliable identification of improved mutants. Herein, we report an approa...
Autores principales: | Vallapurackal, Jaicy, Stucki, Ariane, Liang, Alexandria Deliz, Klehr, Juliane, Dittrich, Petra S., Ward, Thomas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828110/ https://www.ncbi.nlm.nih.gov/pubmed/36130864 http://dx.doi.org/10.1002/anie.202207328 |
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