Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhage

Subarachnoid haemorrhage (SAH) has a high rate of disability and mortality. Extremely damaging molecules, including adenosine triphosphate (ATP), are released from extravasated red blood cells and nerve cells, which activate microglia and induce sterile tissue injury and organ dysfunction. P2X purin...

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Detalles Bibliográficos
Autores principales: Tao, Tao, Chen, Xiangxin, Zhou, Yan, Zheng, Qiang, Gao, Sen, Wang, Jinwei, Ding, Pengfei, Li, Xiaojian, Peng, Zheng, Lu, Yue, Gao, Yongyue, Zhuang, Zong, Hang, Chun‐hua, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828135/
https://www.ncbi.nlm.nih.gov/pubmed/36269673
http://dx.doi.org/10.1111/jnc.15712

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