Cargando…
Thiotemplated Biosynthesis of Bacterial Polyyne Fatty Acids by a Designated Desaturase Triad
Various bacterial species are capable of producing highly modified fatty acid derivatives with conjugated triple bonds, which play important ecological roles as antifungals and toxins in mutualistic and pathogenic interactions. Furthermore, the terminal polyyne moiety is of interest as pharmacophore...
Autores principales: | Kim, Hak Joong, Ishida, Keishi, Hertweck, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828172/ https://www.ncbi.nlm.nih.gov/pubmed/36107027 http://dx.doi.org/10.1002/cbic.202200430 |
Ejemplares similares
-
Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor
por: Trottmann, Felix, et al.
Publicado: (2020) -
Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity
por: Mullins, Alex J., et al.
Publicado: (2021) -
Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy
por: Dunbar, Kyle L., et al.
Publicado: (2020) -
A polyyne toxin produced by an antagonistic bacterium blinds and lyses a Chlamydomonad alga
por: Hotter, Vivien, et al.
Publicado: (2021) -
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids
por: Cerone, Michela, et al.
Publicado: (2022)