Meerwein‐type Bromoarylation with Arylthianthrenium Salts

Herein, we report a photocatalyzed Meerwein‐type bromoarylation of alkenes with stable arylthianthrenium salts, formed by site‐selective C−H thianthrenation. This protocol can be applied to late‐stage functionalization of a variety of biomolecules that are difficult to access by other aryl coupling...

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Detalles Bibliográficos
Autores principales: Cai, Yuan, Ritter, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828184/
https://www.ncbi.nlm.nih.gov/pubmed/36070220
http://dx.doi.org/10.1002/anie.202209882
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author Cai, Yuan
Ritter, Tobias
author_facet Cai, Yuan
Ritter, Tobias
author_sort Cai, Yuan
collection PubMed
description Herein, we report a photocatalyzed Meerwein‐type bromoarylation of alkenes with stable arylthianthrenium salts, formed by site‐selective C−H thianthrenation. This protocol can be applied to late‐stage functionalization of a variety of biomolecules that are difficult to access by other aryl coupling reagents. Halogen introduction allows for a variety of follow‐up transformations, affording numerous biologically active skeletons.
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spelling pubmed-98281842023-01-10 Meerwein‐type Bromoarylation with Arylthianthrenium Salts Cai, Yuan Ritter, Tobias Angew Chem Int Ed Engl Communications Herein, we report a photocatalyzed Meerwein‐type bromoarylation of alkenes with stable arylthianthrenium salts, formed by site‐selective C−H thianthrenation. This protocol can be applied to late‐stage functionalization of a variety of biomolecules that are difficult to access by other aryl coupling reagents. Halogen introduction allows for a variety of follow‐up transformations, affording numerous biologically active skeletons. John Wiley and Sons Inc. 2022-10-20 2022-11-21 /pmc/articles/PMC9828184/ /pubmed/36070220 http://dx.doi.org/10.1002/anie.202209882 Text en © 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Cai, Yuan
Ritter, Tobias
Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title_full Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title_fullStr Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title_full_unstemmed Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title_short Meerwein‐type Bromoarylation with Arylthianthrenium Salts
title_sort meerwein‐type bromoarylation with arylthianthrenium salts
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828184/
https://www.ncbi.nlm.nih.gov/pubmed/36070220
http://dx.doi.org/10.1002/anie.202209882
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