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Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus : PGC7 and UHRF1 regulats IG-DMR methylation

The gene dosage at the imprinted Dlk1-Dio3 locus is critical for cell growth and development. A relatively high gene expression within the Dlk1-Dio3 region, especially the active expression of Gtl2, has been identified as the only reliable marker for cell pluripotency. The DNA methylation state of t...

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Detalles Bibliográficos
Autores principales: Yu, Mengying, Liu, Yingxiang, Han, Zhuo, Du, Wei, Chen, Bingxue, Zhang, Lei, Xue, Hongni, Zhang, Zihan, Guo, Zekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828313/
https://www.ncbi.nlm.nih.gov/pubmed/35866604
http://dx.doi.org/10.3724/abbs.2022080

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