Cargando…
Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus : PGC7 and UHRF1 regulats IG-DMR methylation
The gene dosage at the imprinted Dlk1-Dio3 locus is critical for cell growth and development. A relatively high gene expression within the Dlk1-Dio3 region, especially the active expression of Gtl2, has been identified as the only reliable marker for cell pluripotency. The DNA methylation state of t...
Autores principales: | Yu, Mengying, Liu, Yingxiang, Han, Zhuo, Du, Wei, Chen, Bingxue, Zhang, Lei, Xue, Hongni, Zhang, Zihan, Guo, Zekun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828313/ https://www.ncbi.nlm.nih.gov/pubmed/35866604 http://dx.doi.org/10.3724/abbs.2022080 |
Ejemplares similares
-
Identification of the porcine IG-DMR and abnormal imprinting of DLK1-DIO3 in cloned pigs
por: Li, Junliang, et al.
Publicado: (2022) -
The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period
por: Matsuzaki, Hitomi, et al.
Publicado: (2023) -
Humanization of a tandem repeat in IG-DMR causes stochastic restoration of paternal imprinting at mouse Dlk1-Dio3 domain
por: Hara, Satoshi, et al.
Publicado: (2021) -
Temple syndrome in a patient with variably methylated CpGs at the primary MEG3/DLK1:IG-DMR and severely hypomethylated CpGs at the secondary MEG3:TSS-DMR
por: Kagami, Masayo, et al.
Publicado: (2019) -
PGC7 Regulates Genome-Wide DNA Methylation by Regulating ERK-Mediated Subcellular Localization of DNMT1
por: Wei, Xing, et al.
Publicado: (2023)