Amyloid‐Related Imaging Abnormalities in the DIAN‐TU‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease

OBJECTIVE: To determine the characteristics of participants with amyloid‐related imaging abnormalities (ARIA) in a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease (DIAD). METHODS: 142 DIAD mutation carriers received either gantenerumab SC (n = 52), solanezumab IV (n = ...

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Autores principales: Joseph‐Mathurin, Nelly, Llibre‐Guerra, Jorge J., Li, Yan, McCullough, Austin A., Hofmann, Carsten, Wojtowicz, Jakub, Park, Ethan, Wang, Guoqiao, Preboske, Gregory M., Wang, Qing, Gordon, Brian A., Chen, Charles D., Flores, Shaney, Aggarwal, Neelum T., Berman, Sarah B., Bird, Thomas D., Black, Sandra E., Borowski, Bret, Brooks, William S., Chhatwal, Jasmeer P., Clarnette, Roger, Cruchaga, Carlos, Fagan, Anne M., Farlow, Martin, Fox, Nick C., Gauthier, Serge, Hassenstab, Jason, Hobbs, Diana A., Holdridge, Karen C., Honig, Lawrence S., Hornbeck, Russ C., Hsiung, Ging‐Yuek R., Jack, Clifford R., Jimenez‐Velazquez, Ivonne Z., Jucker, Mathias, Klein, Gregory, Levin, Johannes, Mancini, Michele, Masellis, Mario, McKay, Nicole S., Mummery, Catherine J., Ringman, John M., Shimada, Hiroyuki, Snider, B. Joy, Suzuki, Kazushi, Wallon, David, Xiong, Chengjie, Yaari, Roy, McDade, Eric, Perrin, Richard J., Bateman, Randall J., Salloway, Stephen P., Benzinger, Tammie L.S., Clifford, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828339/
https://www.ncbi.nlm.nih.gov/pubmed/36151869
http://dx.doi.org/10.1002/ana.26511

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