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Solution Structure of a Lanthanide‐binding DNA Aptamer Determined Using High Quality pseudocontact shift restraints

In this contribution we report the high‐resolution NMR structure of a recently identified lanthanide‐binding aptamer (LnA). We demonstrate that the rigid lanthanide binding by LnA allows for the measurement of anisotropic paramagnetic NMR restraints which to date remain largely inaccessible for nucl...

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Detalles Bibliográficos
Autores principales: Andrałojć, Witold, Wieruszewska, Julia, Pasternak, Karol, Gdaniec, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828363/
https://www.ncbi.nlm.nih.gov/pubmed/36043489
http://dx.doi.org/10.1002/chem.202202114

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