Amino acids at position 5 in the peptide/MHC binding region of a public virus‐specific TCR are completely inter‐changeable without loss of function

Anti‐viral T‐cell responses are usually directed against a limited set of antigens, but often contain many T cells expressing different T‐cell receptors (TCRs). Identical TCRs found within virus‐specific T‐cell populations in different individuals are known as public TCRs, but also TCRs highly‐simil...

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Detalles Bibliográficos
Autores principales: Huisman, Wesley, de Gier, Melanie, Hageman, Lois, Shomuradova, Alina S., Leboux, Didier A.T., Amsen, Derk, Falkenburg, J.H. Frederik, Jedema, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Molecular immunology and signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828479/
https://www.ncbi.nlm.nih.gov/pubmed/36189878
http://dx.doi.org/10.1002/eji.202249975

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