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Design, Synthesis, and in Vitro Evaluation of 4‐(4‐Hydroxyphenyl)piperazine‐Based Compounds Targeting Tyrosinase

Melanin biosynthesis is enzymatically regulated by tyrosinase (TYR, EC 1.14.18.1), which is efficiently inhibited by natural and synthetic phenols, demonstrating potential therapeutic application for the treatment of several human diseases. Herein we report the inhibitory effects of a series of (4‐(...

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Detalles Bibliográficos
Autores principales:	Mirabile, Salvatore, Germanò, Maria Paola, Fais, Antonella, Lombardo, Lisa, Ricci, Federico, Floris, Sonia, Cacciola, Anna, Rapisarda, Antonio, Gitto, Rosaria, De Luca, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828493/ https://www.ncbi.nlm.nih.gov/pubmed/36093940 http://dx.doi.org/10.1002/cmdc.202200305

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