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Substantial gradient mitigation in simulated large‐scale bioreactors by optimally placed multiple feed points
The performance of large‐scale stirred tank and bubble column bioreactors is often hindered by insufficient macromixing of feeds, leading to heterogeneities in pH, substrate, and oxygen, which complicates process scale‐up. Appropriate feed placement or the use of multiple feed points could improve m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828524/ https://www.ncbi.nlm.nih.gov/pubmed/36110051 http://dx.doi.org/10.1002/bit.28232 |