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Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018
AIM: To describe adults with (non‐dialysis) chronic kidney disease (CKD) in nine public renal practice sites in the Australian state of Queensland. METHODS: 7,060 persons were recruited to a CKD Registry in May 2011 and until start of kidney replacement therapy (KRT), death without KRT or June 2018,...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828529/ https://www.ncbi.nlm.nih.gov/pubmed/36161428 http://dx.doi.org/10.1111/nep.14111 |
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author | Hoy, Wendy E. Wang, Zaimin Zhang, Jianzhen Diwan, Vishal Cameron, Anne Venuthurupalli, Sree K. Fassett, Robert G. Chan, Samuel Healy, Helen G. Tan, Ken‐Soon Baer, Richard Mallett, Andrew J. Gray, Nicholas Mantha, Murty Cherian, Roy Mutatiri, Clyson Madhan, Krishan Kan, George Mitchell, Geoffrey Hossain, Shahadat Wu, Danielle Han, Thin Kark, Adrian Titus, Thomas Ranganathan, Dwarakanatan Bonner, Ann Govindarajulu, Sridevi |
author_facet | Hoy, Wendy E. Wang, Zaimin Zhang, Jianzhen Diwan, Vishal Cameron, Anne Venuthurupalli, Sree K. Fassett, Robert G. Chan, Samuel Healy, Helen G. Tan, Ken‐Soon Baer, Richard Mallett, Andrew J. Gray, Nicholas Mantha, Murty Cherian, Roy Mutatiri, Clyson Madhan, Krishan Kan, George Mitchell, Geoffrey Hossain, Shahadat Wu, Danielle Han, Thin Kark, Adrian Titus, Thomas Ranganathan, Dwarakanatan Bonner, Ann Govindarajulu, Sridevi |
author_sort | Hoy, Wendy E. |
collection | PubMed |
description | AIM: To describe adults with (non‐dialysis) chronic kidney disease (CKD) in nine public renal practice sites in the Australian state of Queensland. METHODS: 7,060 persons were recruited to a CKD Registry in May 2011 and until start of kidney replacement therapy (KRT), death without KRT or June 2018, for a median period of 3.4 years. RESULTS: The cohort comprised 7,060 persons, 52% males, with a median age of 68 yr; 85% had CKD stages 3A to 5, 45.4% were diabetic, 24.6% had diabetic nephropathy, and 51.7% were obese. Younger persons mostly had glomerulonephritis or genetic renal disease, while older persons mostly had diabetic nephropathy, renovascular disease and multiple diagnoses. Proportions of specific renal diagnoses varied >2‐fold across sites. Over the first year, eGFR fell in 24% but was stable or improved in 76%. Over follow up, 10% started KRT, at a median age of 62 yr, most with CKD stages 4 and 5 at consent, while 18.8% died without KRT, at a median age of 80 yr. Indigenous people were younger at consent and more often had diabetes and diabetic kidney disease and had higher incidence rates of KRT. CONCLUSION: The spectrum of characteristics in CKD patients in renal practices is much broader than represented by the minority who ultimately start KRT. Variation in CKD by causes, age, site and Indigenous status, the prevalence of obesity, relative stability of kidney function in many persons over the short term, and differences between those who KRT and die without KRT are all important to explore. |
format | Online Article Text |
id | pubmed-9828529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons Australia, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-98285292023-01-10 Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 Hoy, Wendy E. Wang, Zaimin Zhang, Jianzhen Diwan, Vishal Cameron, Anne Venuthurupalli, Sree K. Fassett, Robert G. Chan, Samuel Healy, Helen G. Tan, Ken‐Soon Baer, Richard Mallett, Andrew J. Gray, Nicholas Mantha, Murty Cherian, Roy Mutatiri, Clyson Madhan, Krishan Kan, George Mitchell, Geoffrey Hossain, Shahadat Wu, Danielle Han, Thin Kark, Adrian Titus, Thomas Ranganathan, Dwarakanatan Bonner, Ann Govindarajulu, Sridevi Nephrology (Carlton) Chronic Kidney Disease AIM: To describe adults with (non‐dialysis) chronic kidney disease (CKD) in nine public renal practice sites in the Australian state of Queensland. METHODS: 7,060 persons were recruited to a CKD Registry in May 2011 and until start of kidney replacement therapy (KRT), death without KRT or June 2018, for a median period of 3.4 years. RESULTS: The cohort comprised 7,060 persons, 52% males, with a median age of 68 yr; 85% had CKD stages 3A to 5, 45.4% were diabetic, 24.6% had diabetic nephropathy, and 51.7% were obese. Younger persons mostly had glomerulonephritis or genetic renal disease, while older persons mostly had diabetic nephropathy, renovascular disease and multiple diagnoses. Proportions of specific renal diagnoses varied >2‐fold across sites. Over the first year, eGFR fell in 24% but was stable or improved in 76%. Over follow up, 10% started KRT, at a median age of 62 yr, most with CKD stages 4 and 5 at consent, while 18.8% died without KRT, at a median age of 80 yr. Indigenous people were younger at consent and more often had diabetes and diabetic kidney disease and had higher incidence rates of KRT. CONCLUSION: The spectrum of characteristics in CKD patients in renal practices is much broader than represented by the minority who ultimately start KRT. Variation in CKD by causes, age, site and Indigenous status, the prevalence of obesity, relative stability of kidney function in many persons over the short term, and differences between those who KRT and die without KRT are all important to explore. John Wiley & Sons Australia, Ltd 2022-10-09 2022-12 /pmc/articles/PMC9828529/ /pubmed/36161428 http://dx.doi.org/10.1111/nep.14111 Text en © 2022 The Authors. Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Chronic Kidney Disease Hoy, Wendy E. Wang, Zaimin Zhang, Jianzhen Diwan, Vishal Cameron, Anne Venuthurupalli, Sree K. Fassett, Robert G. Chan, Samuel Healy, Helen G. Tan, Ken‐Soon Baer, Richard Mallett, Andrew J. Gray, Nicholas Mantha, Murty Cherian, Roy Mutatiri, Clyson Madhan, Krishan Kan, George Mitchell, Geoffrey Hossain, Shahadat Wu, Danielle Han, Thin Kark, Adrian Titus, Thomas Ranganathan, Dwarakanatan Bonner, Ann Govindarajulu, Sridevi Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title | Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title_full | Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title_fullStr | Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title_full_unstemmed | Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title_short | Chronic kidney disease in public renal practices in Queensland, Australia, 2011–2018 |
title_sort | chronic kidney disease in public renal practices in queensland, australia, 2011–2018 |
topic | Chronic Kidney Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828529/ https://www.ncbi.nlm.nih.gov/pubmed/36161428 http://dx.doi.org/10.1111/nep.14111 |
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