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Pilot scale production and characterization of next generation high molecular weight and tense quaternary state polymerized human hemoglobin

Polymerized human hemoglobin (PolyhHb) is being studied as a possible red blood cell (RBC) substitute for use in scenarios where blood is not available. While the oxygen (O(2)) carrying capacity of PolyhHb makes it appealing as an O(2) therapeutic, the commercial PolyhHb PolyHeme® (Northfield Labora...

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Detalles Bibliográficos
Autores principales:	Cuddington, Clayton T., Wolfe, Savannah R., Belcher, Donald A., Allyn, Megan, Greenfield, Alisyn, Gu, Xiangming, Hickey, Richard, Lu, Shuwei, Salvi, Tanmay, Palmer, Andre F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828582/ https://www.ncbi.nlm.nih.gov/pubmed/36120842 http://dx.doi.org/10.1002/bit.28233

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