Translesion synthesis of apurinic/apyrimidic siteanalogues by Y-family DNA polymerase Dbh from Sulfolobus acidocaldarius : Translesion synthesis of apurinic/apyrimidic site analogues

Apurinic/apyrimidic (AP) sites are severe DNA damages and strongly block DNA extension by major DNA polymerases. Y-family DNA polymerases possess a strong ability to bypass AP sites and continue the DNA synthesis reaction, which is called translesion synthesis (TLS) activity. To investigate the effe...

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Detalles Bibliográficos
Autores principales: Wang, Weiwei, Zhou, Huan, Peng, Li, Yu, Feng, Xu, Qin, Wang, Qisheng, He, Jianhua, Liu, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828665/
https://www.ncbi.nlm.nih.gov/pubmed/35920197
http://dx.doi.org/10.3724/abbs.2022045

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