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Mechanisms of development and progression of pancreatic neoplasms

Pancreatic ductal adenocarcinoma (PDAC) develops via dysplastic changes in the epithelia graded as low‐ and high‐grade with accumulation of molecular alterations. Constitutive activation of mitogen‐activated protein kinase (MAPK) contributed by attenuation of DUSP6 plays a key role in sustaining PDA...

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Detalles Bibliográficos
Autor principal: Furukawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828726/
https://www.ncbi.nlm.nih.gov/pubmed/36161420
http://dx.doi.org/10.1111/pin.13272