Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma

Cancer‐associated fibroblasts (CAFs) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Previously we described four CAF subtypes with specific molecular and functional features. Here, we have refined our CAF subtype signatures using RNAseq and immunostaining with the...

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Detalles Bibliográficos
Autores principales: Neuzillet, Cindy, Nicolle, Rémy, Raffenne, Jérôme, Tijeras‐Raballand, Annemilaï, Brunel, Alexia, Astorgues‐Xerri, Lucile, Vacher, Sophie, Arbateraz, Floriane, Fanjul, Marjorie, Hilmi, Marc, Samain, Rémi, Klein, Christophe, Perraud, Aurélie, Rebours, Vinciane, Mathonnet, Muriel, Bièche, Ivan, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828775/
https://www.ncbi.nlm.nih.gov/pubmed/36102377
http://dx.doi.org/10.1002/path.6011

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