Anti‐CD38 monoclonal antibody interference with blood compatibility testing: Differentiating isatuximab and daratumumab via functional epitope mapping

BACKGROUND: There are two FDA‐approved anti‐CD38 monoclonal antibodies for treatment of multiple myeloma: isatuximab and daratumumab. Owing to expression of CD38 on reagent red blood cells (RBCs), these antibodies interfere with indirect antiglobulin tests (IATs). We sought to understand differences...

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Detalles Bibliográficos
Autores principales: Chami, Btissam, Okuda, Makoto, Moayeri, Morvarid, Pirenne, France, Hidaka, Yoko, Nambiar, Ashok, Song, Zhili, Bedel, Olivier, Zhang, Bailin, Hopke, Joern, Deng, Gejing, Zhu, Chen, Macé, Sandrine, Chiron, Marielle, Adrian, Francisco, Fukao, Taro, Basile, Frank G., Martin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Immunohematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828815/
https://www.ncbi.nlm.nih.gov/pubmed/36239134
http://dx.doi.org/10.1111/trf.17137

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