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Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer
The aim of our study was to validate the use of the standardized Radiological Society of North America (RSNA) reporting system in individuals with known lung cancer who presented to the emergency department with suspected COVID-19. We included patients aged 18 years or older from the Cancer Institut...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828872/ https://www.ncbi.nlm.nih.gov/pubmed/36629525 http://dx.doi.org/10.1590/1414-431X2022e12376 |
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author | Peixoto, D. Neves, Y.C.S. Generoso, G. Loureiro, B.M.C. Callia, J.P.B. Anastácio, V.M. Alves, J.L. Oshiro, E.M. Lima, L.R. Sawamura, M.V.Y. Auad, R.V. Bittencourt, M.S. Abdala, E. Ibrahim, K.Y. |
author_facet | Peixoto, D. Neves, Y.C.S. Generoso, G. Loureiro, B.M.C. Callia, J.P.B. Anastácio, V.M. Alves, J.L. Oshiro, E.M. Lima, L.R. Sawamura, M.V.Y. Auad, R.V. Bittencourt, M.S. Abdala, E. Ibrahim, K.Y. |
author_sort | Peixoto, D. |
collection | PubMed |
description | The aim of our study was to validate the use of the standardized Radiological Society of North America (RSNA) reporting system in individuals with known lung cancer who presented to the emergency department with suspected COVID-19. We included patients aged 18 years or older from the Cancer Institute of the State of São Paulo (ICESP) with a confirmed diagnosis of lung cancer, admitted to the emergency department and undergoing chest computed tomography (CT) for suspicion of COVID-19. Comparison between SARS-CoV2 RT-PCR across RSNA categories was performed in all patients and further stratified by diagnosis of lung cancer progression. Among 58 individuals included in the analysis (65±9 years, 43% men), 20 had positive RT-PCR. Less than a half (43%) had no new lung findings in the CT. Positive RT-PCR was present in 75% of those with typical findings according to RSNA and in only 9% when these findings were classified as atypical or negative (P<0.001). Diagnostic accuracy was even higher when stratified by the presence or absence of progressive disease (PD). Extent of pulmonary inflammatory changes was strongly associated with higher mortality, reaching a lethality of 83% in patients with >25% of lung involvement and 100% when there was >50% of lung involvement. The lung involvement score was also highly predictive of prognosis in this population as was reported for non-lung cancer individuals. Collectively, our results demonstrated that diagnostic and prognostic values of chest CT findings in COVID-19 are robust to the presence of lung abnormalities related to lung cancer. |
format | Online Article Text |
id | pubmed-9828872 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Associação Brasileira de Divulgação Científica |
record_format | MEDLINE/PubMed |
spelling | pubmed-98288722023-01-10 Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer Peixoto, D. Neves, Y.C.S. Generoso, G. Loureiro, B.M.C. Callia, J.P.B. Anastácio, V.M. Alves, J.L. Oshiro, E.M. Lima, L.R. Sawamura, M.V.Y. Auad, R.V. Bittencourt, M.S. Abdala, E. Ibrahim, K.Y. Braz J Med Biol Res Research Article The aim of our study was to validate the use of the standardized Radiological Society of North America (RSNA) reporting system in individuals with known lung cancer who presented to the emergency department with suspected COVID-19. We included patients aged 18 years or older from the Cancer Institute of the State of São Paulo (ICESP) with a confirmed diagnosis of lung cancer, admitted to the emergency department and undergoing chest computed tomography (CT) for suspicion of COVID-19. Comparison between SARS-CoV2 RT-PCR across RSNA categories was performed in all patients and further stratified by diagnosis of lung cancer progression. Among 58 individuals included in the analysis (65±9 years, 43% men), 20 had positive RT-PCR. Less than a half (43%) had no new lung findings in the CT. Positive RT-PCR was present in 75% of those with typical findings according to RSNA and in only 9% when these findings were classified as atypical or negative (P<0.001). Diagnostic accuracy was even higher when stratified by the presence or absence of progressive disease (PD). Extent of pulmonary inflammatory changes was strongly associated with higher mortality, reaching a lethality of 83% in patients with >25% of lung involvement and 100% when there was >50% of lung involvement. The lung involvement score was also highly predictive of prognosis in this population as was reported for non-lung cancer individuals. Collectively, our results demonstrated that diagnostic and prognostic values of chest CT findings in COVID-19 are robust to the presence of lung abnormalities related to lung cancer. Associação Brasileira de Divulgação Científica 2023-01-09 /pmc/articles/PMC9828872/ /pubmed/36629525 http://dx.doi.org/10.1590/1414-431X2022e12376 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Peixoto, D. Neves, Y.C.S. Generoso, G. Loureiro, B.M.C. Callia, J.P.B. Anastácio, V.M. Alves, J.L. Oshiro, E.M. Lima, L.R. Sawamura, M.V.Y. Auad, R.V. Bittencourt, M.S. Abdala, E. Ibrahim, K.Y. Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title | Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title_full | Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title_fullStr | Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title_full_unstemmed | Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title_short | Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer |
title_sort | validation of the north america expert consensus statement on reporting ct findings for covid-19 in individuals with lung cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828872/ https://www.ncbi.nlm.nih.gov/pubmed/36629525 http://dx.doi.org/10.1590/1414-431X2022e12376 |
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