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Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report

Respiratory symptoms and signs remain the hallmark of coronavirus disease 2019 (COVID-19) infection. However, extrapulmonary manifestations of COVID-19 are not uncommon, and are likely to be underreported. The present study describes a clinical case of a 64-year-old patient with COVID-19 with marked...

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Autores principales: Khalid, Karniza, Ab Wahab, Suhaila, Azni, Khaulah Karimah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829092/
https://www.ncbi.nlm.nih.gov/pubmed/36698532
http://dx.doi.org/10.3892/mi.2021.24
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author Khalid, Karniza
Ab Wahab, Suhaila
Azni, Khaulah Karimah
author_facet Khalid, Karniza
Ab Wahab, Suhaila
Azni, Khaulah Karimah
author_sort Khalid, Karniza
collection PubMed
description Respiratory symptoms and signs remain the hallmark of coronavirus disease 2019 (COVID-19) infection. However, extrapulmonary manifestations of COVID-19 are not uncommon, and are likely to be underreported. The present study describes a clinical case of a 64-year-old patient with COVID-19 with marked extrapulmonary manifestations in the setting of strong positive reactions with cycle threshold values of reverse transcription polymerase chain reaction for COVID-19. He presented with asymptomatic bradycardia with wide pulse pressure, eventually requiring transvenous cardiac pacing. He later complained of lower abdominal pain associated with no bowel movements for four days. The computed tomography examination of the abdomen revealed circumferential wall thickening at the proximal ascending colon, suggestive of inflammatory changes and features of obstruction in the presence of inguinal hernia. Despite aggressive resuscitative efforts, the patient continued to deteriorate with multiorgan failure, and eventually succumbed to the disease after 6 days of hospitalization. The present case study deliberates the sharing of our clinical experience and therapeutic challenges in the management of COVID-19 with complex extrapulmonary manifestation.
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spelling pubmed-98290922023-01-24 Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report Khalid, Karniza Ab Wahab, Suhaila Azni, Khaulah Karimah Med Int (Lond) Case Report Respiratory symptoms and signs remain the hallmark of coronavirus disease 2019 (COVID-19) infection. However, extrapulmonary manifestations of COVID-19 are not uncommon, and are likely to be underreported. The present study describes a clinical case of a 64-year-old patient with COVID-19 with marked extrapulmonary manifestations in the setting of strong positive reactions with cycle threshold values of reverse transcription polymerase chain reaction for COVID-19. He presented with asymptomatic bradycardia with wide pulse pressure, eventually requiring transvenous cardiac pacing. He later complained of lower abdominal pain associated with no bowel movements for four days. The computed tomography examination of the abdomen revealed circumferential wall thickening at the proximal ascending colon, suggestive of inflammatory changes and features of obstruction in the presence of inguinal hernia. Despite aggressive resuscitative efforts, the patient continued to deteriorate with multiorgan failure, and eventually succumbed to the disease after 6 days of hospitalization. The present case study deliberates the sharing of our clinical experience and therapeutic challenges in the management of COVID-19 with complex extrapulmonary manifestation. D.A. Spandidos 2021-12-07 /pmc/articles/PMC9829092/ /pubmed/36698532 http://dx.doi.org/10.3892/mi.2021.24 Text en Copyright: © Khalid et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Khalid, Karniza
Ab Wahab, Suhaila
Azni, Khaulah Karimah
Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title_full Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title_fullStr Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title_full_unstemmed Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title_short Therapeutic challenges of extrapulmonary dual organ system involvement in COVID-19: A case report
title_sort therapeutic challenges of extrapulmonary dual organ system involvement in covid-19: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829092/
https://www.ncbi.nlm.nih.gov/pubmed/36698532
http://dx.doi.org/10.3892/mi.2021.24
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