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The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment
Invasive aspergillosis remains one of the most devastating fungal diseases and is predominantly linked to infections caused by the opportunistic human mold pathogen Aspergillus fumigatus. Major treatment regimens for the disease comprise the administration of antifungals belonging to the azole, poly...
Autores principales: | Sastré-Velásquez, Luis Enrique, Dallemulle, Alex, Kühbacher, Alexander, Baldin, Clara, Alcazar-Fuoli, Laura, Niedrig, Anna, Müller, Christoph, Gsaller, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829169/ https://www.ncbi.nlm.nih.gov/pubmed/36574449 http://dx.doi.org/10.1371/journal.ppat.1011066 |
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