Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis

Variation in immune homeostasis, the state in which the immune system is maintained in the absence of stimulation, is highly variable across populations. This variation is attributed to both genetic and environmental factors. However, the identity and function of specific regulators have been diffic...

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Detalles Bibliográficos
Autores principales: Hampton, Brea K., Plante, Kenneth S., Whitmore, Alan C., Linnertz, Colton L., Madden, Emily A., Noll, Kelsey E., Boyson, Samuel P., Parotti, Breantie, Xenakis, James G., Bell, Timothy A., Hock, Pablo, Shaw, Ginger D., de Villena, Fernando Pardo-Manuel, Ferris, Martin T., Heise, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829176/
https://www.ncbi.nlm.nih.gov/pubmed/36574452
http://dx.doi.org/10.1371/journal.pgen.1010548

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