Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens

Genome-wide genetic screens are powerful tools to identify genes that act as host factors of viruses. We have applied this technique to analyze the infection of HeLa cells by Vaccinia virus, in an attempt to find genes necessary for infection. Infection of cell populations harboring single gene inac...

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Detalles Bibliográficos
Autores principales: Matía, Alejandro, Lorenzo, Maria M., Romero-Estremera, Yolimar C., Sánchez-Puig, Juana M., Zaballos, Angel, Blasco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829182/
https://www.ncbi.nlm.nih.gov/pubmed/36574441
http://dx.doi.org/10.1371/journal.ppat.1010800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829182/
https://www.ncbi.nlm.nih.gov/pubmed/36574441
http://dx.doi.org/10.1371/journal.ppat.1010800

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