Cargando…

Stress combined with loss of the Candida albicans SUMO protease Ulp2 triggers selection of aneuploidy via a two-step process

A delicate balance between genome stability and instability ensures genome integrity while generating genetic diversity, a critical step for evolution. Indeed, while excessive genome instability is harmful, moderated genome instability can drive adaptation to novel environments by maximising genetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rizzo, Marzia, Soisangwan, Natthapon, Vega-Estevez, Samuel, Price, Robert Jordan, Uyl, Chloe, Iracane, Elise, Shaw, Matt, Soetaert, Jan, Selmecki, Anna, Buscaino, Alessia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829183/ https://www.ncbi.nlm.nih.gov/pubmed/36574460 http://dx.doi.org/10.1371/journal.pgen.1010576

Ejemplares similares

Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy
por: Ryu, Hong-Yeoul, et al.
Publicado: (2016)

On and Off: Epigenetic Regulation of C. albicans Morphological Switches
por: Iracane, Elise, et al.
Publicado: (2021)

Antifungal Drug Concentration Impacts the Spectrum of Adaptive Mutations in Candida albicans
por: Todd, Robert T, et al.
Publicado: (2023)

Sumo-dependent substrate targeting of the SUMO protease Ulp1
por: Elmore, Zachary C, et al.
Publicado: (2011)

Distinct adaptive mechanisms drive recovery from aneuploidy caused by loss of the Ulp2 SUMO protease
por: Ryu, Hong-Yeoul, et al.
Publicado: (2018)

SUMO targeting of a stress-tolerant Ulp1 SUMO protease
por: Peek, Jennifer, et al.
Publicado: (2018)

Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo
por: Burrack, Laura S., et al.
Publicado: (2022)

The S. pombe Translation Initiation Factor eIF4G Is Sumoylated and Associates with the SUMO Protease Ulp2
por: Jongjitwimol, Jirapas, et al.
Publicado: (2014)

Susceptibility to Medium-Chain Fatty Acids Is Associated with Trisomy of Chromosome 7 in Candida albicans
por: Ma, Qinxi, et al.
Publicado: (2019)

SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension
por: Gao, Kaiyu, et al.
Publicado: (2019)

Immobilization of Ulp1 protease on NHS-activated Sepharose: a useful tool for cleavage of the SUMO tag of recombinant proteins
por: Liang, Qiujin, et al.
Publicado: (2017)

Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS–PSSC System to Advance the Conserved Mechanism for Substrate Cleavage
por: Zhang, Faying, et al.
Publicado: (2022)

Correction for Ma et al., “Susceptibility to Medium-Chain Fatty Acids Is Associated with Trisomy of Chromosome 7 in Candida albicans”
por: Ma, Qinxi, et al.
Publicado: (2019)

The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity
por: Li, Shyr-Jiann, et al.
Publicado: (2003)

A simple and rapid protein purification method based on cell-surface display of SUMO-fused recombinant protein and Ulp1 protease
por: Zhou, Xiao-Feng, et al.
Publicado: (2020)

Tunicamycin Potentiates Antifungal Drug Tolerance via Aneuploidy in Candida albicans
por: Yang, Feng, et al.
Publicado: (2021)

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans
por: Kakade, Pallavi, et al.
Publicado: (2023)

Genome plasticity in Candida albicans is driven by long repeat sequences
por: Todd, Robert T, et al.
Publicado: (2019)

The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin
por: Freire-Benéitez, Verónica, et al.
Publicado: (2016)

The SUMO Isopeptidase Ulp2p Is Required to Prevent Recombination-Induced Chromosome Segregation Lethality following DNA Replication Stress
por: Lee, Ming-Ta, et al.
Publicado: (2011)

A Novel Strategy for the Preparation of Codon-Optimized Truncated Ulp1 and its Simplified Application to Cleavage the SUMO Fusion Protein
por: Wang, Xiaohua, et al.
Publicado: (2016)

Arabidopsis thaliana SPF1 and SPF2 are nuclear-located ULP2-like SUMO proteases that act downstream of SIZ1 in plant development
por: Castro, Pedro Humberto, et al.
Publicado: (2018)

Widespread occurrence of chromosomal aneuploidy following the routine production of Candida albicans mutants
por: Arbour, Mélanie, et al.
Publicado: (2009)

The role of aneuploidy in the emergence of echinocandin resistance in human fungal pathogen Candida albicans
por: Sah, Sudisht Kumar, et al.
Publicado: (2021)

Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole
por: Kukurudz, Rebekah J, et al.
Publicado: (2022)

Aneuploidy Mediates Rapid Adaptation to a Subinhibitory Amount of Fluconazole in Candida albicans
por: Sun, Liu-liu, et al.
Publicado: (2023)

Candida albicans repetitive elements display epigenetic diversity and plasticity
por: Freire-Benéitez, Verónica, et al.
Publicado: (2016)

Chromatin Profiling of the Repetitive and Nonrepetitive Genomes of the Human Fungal Pathogen Candida albicans
por: Price, Robert Jordan, et al.
Publicado: (2019)

Sir2 regulates stability of repetitive domains differentially in the human fungal pathogen Candida albicans
por: Freire-Benéitez, Verónica, et al.
Publicado: (2016)

Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans
por: Hickman, Meleah A., et al.
Publicado: (2015)

Neocentromeres Form Efficiently at Multiple Possible Loci in Candida albicans
por: Ketel, Carrie, et al.
Publicado: (2009)

Low Dosage of Histone H4 Leads to Growth Defects and Morphological Changes in Candida albicans
por: Zacchi, Lucia F., et al.
Publicado: (2010)

Revised nomenclature and functional overview of the ULP gene family of plant deSUMOylating proteases
por: Castro, Pedro Humberto, et al.
Publicado: (2018)

Candida albicans Strains Adapted to Caspofungin Due to Aneuploidy Become Highly Tolerant under Continued Drug Pressure
por: Husain, Farha, et al.
Publicado: (2022)

The Dynamic Fungal Genome: Polyploidy, Aneuploidy and Copy Number Variation in Response to Stress
por: Vande Zande, Pétra, et al.
Publicado: (2023)

Identification of an Exceptionally Long Intron in the HAC1 Gene of Candida parapsilosis
por: Iracane, Elise, et al.
Publicado: (2018)

Butterfly: μW Level ULP Sensor Nodes with High Task Throughput
por: Zhang, Chong, et al.
Publicado: (2022)

Recruitment of the Ulp2 protease to the inner kinetochore prevents its hyper-sumoylation to ensure accurate chromosome segregation
por: Suhandynata, Raymond T., et al.
Publicado: (2019)

Correlating Genotype and Phenotype in the Asexual Yeast Candida orthopsilosis Implicates ZCF29 in Sensitivity to Caffeine
por: de San Vicente, Kontxi Martinez, et al.
Publicado: (2019)

Multi-species biofilm of Candida albicans and non-Candida albicans Candida species on acrylic substrate
por: K PATHAK, Apurva, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0rs1mlg2lsss2f55mjv8nae234