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Na+/K+‑ATPase subunit α3 expression is associated with the efficacy of digitoxin treatment in pancreatic cancer cells

The alpha subunits (ATP1A1-3) of Na(+)/K(+)-ATPase binds digitoxin with varying affinity. The expression levels of these subunits dictate the anticancer effects of digitoxin. In the present study, three pancreatic cancer cell lines, AsPC-1, Panc-1 and CFPAC-1, were used to investigate the effects of...

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Detalles Bibliográficos
Autores principales:	Lindholm, Heléne, Ejeskär, Katarina, Szekeres, Ferenc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829214/ https://www.ncbi.nlm.nih.gov/pubmed/36698913 http://dx.doi.org/10.3892/mi.2022.52

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