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Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase

Selaginella moellendorffii miltiradiene synthase (SmMDS) is a unique bifunctional diterpene synthase (diTPS) that catalyses the successive cyclization of (E,E,E)‐geranylgeranyl diphosphate (GGPP) via (+)‐copalyl diphosphate (CPP) to miltiradiene, which is a crucial precursor of important medicinal c...

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Detalles Bibliográficos
Autores principales: Tong, Yuru, Ma, Xiaoli, Hu, Tianyuan, Chen, Kang, Cui, Guanghong, Su, Ping, Xu, Haifeng, Gao, Wei, Jiang, Tao, Huang, Luqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829396/
https://www.ncbi.nlm.nih.gov/pubmed/36161753
http://dx.doi.org/10.1111/pbi.13933