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Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase
Selaginella moellendorffii miltiradiene synthase (SmMDS) is a unique bifunctional diterpene synthase (diTPS) that catalyses the successive cyclization of (E,E,E)‐geranylgeranyl diphosphate (GGPP) via (+)‐copalyl diphosphate (CPP) to miltiradiene, which is a crucial precursor of important medicinal c...
Autores principales: | Tong, Yuru, Ma, Xiaoli, Hu, Tianyuan, Chen, Kang, Cui, Guanghong, Su, Ping, Xu, Haifeng, Gao, Wei, Jiang, Tao, Huang, Luqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829396/ https://www.ncbi.nlm.nih.gov/pubmed/36161753 http://dx.doi.org/10.1111/pbi.13933 |
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