Cargando…

Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant

Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19–related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Sadia Z., Alvarez, Francisco G., Sanghavi, Devang K., Moreno Franco, Pablo, Isha, Shahin, Marquez, Christopher P., Libertin, Claudia, Guru, Pramod K., Sareyyupoglu, Basar, Pham, Si M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829600/
https://www.ncbi.nlm.nih.gov/pubmed/36644594
http://dx.doi.org/10.1016/j.mayocpiqo.2023.01.001
Descripción
Sumario:Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19–related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe a pitfall of presumed prolonged shedding of SARS-CoV-2 in a patient with COVID-19 associated acute respiratory distress syndrome leading to COVID-19 pneumonia after lung transplant. This raises concerns that replication-competent SARS-CoV-2 virus can persist for months post-infection and can lead to re-infection of grafts in the future.