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Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant

Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19–related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty...

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Autores principales: Shah, Sadia Z., Alvarez, Francisco G., Sanghavi, Devang K., Moreno Franco, Pablo, Isha, Shahin, Marquez, Christopher P., Libertin, Claudia, Guru, Pramod K., Sareyyupoglu, Basar, Pham, Si M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829600/
https://www.ncbi.nlm.nih.gov/pubmed/36644594
http://dx.doi.org/10.1016/j.mayocpiqo.2023.01.001
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author Shah, Sadia Z.
Alvarez, Francisco G.
Sanghavi, Devang K.
Moreno Franco, Pablo
Isha, Shahin
Marquez, Christopher P.
Libertin, Claudia
Guru, Pramod K.
Sareyyupoglu, Basar
Pham, Si M.
author_facet Shah, Sadia Z.
Alvarez, Francisco G.
Sanghavi, Devang K.
Moreno Franco, Pablo
Isha, Shahin
Marquez, Christopher P.
Libertin, Claudia
Guru, Pramod K.
Sareyyupoglu, Basar
Pham, Si M.
author_sort Shah, Sadia Z.
collection PubMed
description Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19–related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe a pitfall of presumed prolonged shedding of SARS-CoV-2 in a patient with COVID-19 associated acute respiratory distress syndrome leading to COVID-19 pneumonia after lung transplant. This raises concerns that replication-competent SARS-CoV-2 virus can persist for months post-infection and can lead to re-infection of grafts in the future.
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spelling pubmed-98296002023-01-10 Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant Shah, Sadia Z. Alvarez, Francisco G. Sanghavi, Devang K. Moreno Franco, Pablo Isha, Shahin Marquez, Christopher P. Libertin, Claudia Guru, Pramod K. Sareyyupoglu, Basar Pham, Si M. Mayo Clin Proc Innov Qual Outcomes Case Report Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19–related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe a pitfall of presumed prolonged shedding of SARS-CoV-2 in a patient with COVID-19 associated acute respiratory distress syndrome leading to COVID-19 pneumonia after lung transplant. This raises concerns that replication-competent SARS-CoV-2 virus can persist for months post-infection and can lead to re-infection of grafts in the future. Elsevier 2023-01-10 /pmc/articles/PMC9829600/ /pubmed/36644594 http://dx.doi.org/10.1016/j.mayocpiqo.2023.01.001 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shah, Sadia Z.
Alvarez, Francisco G.
Sanghavi, Devang K.
Moreno Franco, Pablo
Isha, Shahin
Marquez, Christopher P.
Libertin, Claudia
Guru, Pramod K.
Sareyyupoglu, Basar
Pham, Si M.
Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title_full Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title_fullStr Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title_full_unstemmed Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title_short Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant
title_sort coronavirus disease 2019 causing infection of transplanted lung allograft: a pitfall of prolonged shedding of severe acute respiratory syndrome coronavirus-2 pretransplant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829600/
https://www.ncbi.nlm.nih.gov/pubmed/36644594
http://dx.doi.org/10.1016/j.mayocpiqo.2023.01.001
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