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Coronavirus covid-19 detection by means of explainable deep learning
The coronavirus is caused by the infection of the SARS-CoV-2 virus: it represents a complex and new condition, considering that until the end of December 2019 this virus was totally unknown to the international scientific community. The clinical management of patients with the coronavirus disease ha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830129/ https://www.ncbi.nlm.nih.gov/pubmed/36627339 http://dx.doi.org/10.1038/s41598-023-27697-y |
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author | Mercaldo, Francesco Belfiore, Maria Paola Reginelli, Alfonso Brunese, Luca Santone, Antonella |
author_facet | Mercaldo, Francesco Belfiore, Maria Paola Reginelli, Alfonso Brunese, Luca Santone, Antonella |
author_sort | Mercaldo, Francesco |
collection | PubMed |
description | The coronavirus is caused by the infection of the SARS-CoV-2 virus: it represents a complex and new condition, considering that until the end of December 2019 this virus was totally unknown to the international scientific community. The clinical management of patients with the coronavirus disease has undergone an evolution over the months, thanks to the increasing knowledge of the virus, symptoms and efficacy of the various therapies. Currently, however, there is no specific therapy for SARS-CoV-2 virus, know also as Coronavirus disease 19, and treatment is based on the symptoms of the patient taking into account the overall clinical picture. Furthermore, the test to identify whether a patient is affected by the virus is generally performed on sputum and the result is generally available within a few hours or days. Researches previously found that the biomedical imaging analysis is able to show signs of pneumonia. For this reason in this paper, with the aim of providing a fully automatic and faster diagnosis, we design and implement a method adopting deep learning for the novel coronavirus disease detection, starting from computed tomography medical images. The proposed approach is aimed to detect whether a computed tomography medical images is related to an healthy patient, to a patient with a pulmonary disease or to a patient affected with Coronavirus disease 19. In case the patient is marked by the proposed method as affected by the Coronavirus disease 19, the areas symptomatic of the Coronavirus disease 19 infection are automatically highlighted in the computed tomography medical images. We perform an experimental analysis to empirically demonstrate the effectiveness of the proposed approach, by considering medical images belonging from different institutions, with an average time for Coronavirus disease 19 detection of approximately 8.9 s and an accuracy equal to 0.95. |
format | Online Article Text |
id | pubmed-9830129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-98301292023-01-10 Coronavirus covid-19 detection by means of explainable deep learning Mercaldo, Francesco Belfiore, Maria Paola Reginelli, Alfonso Brunese, Luca Santone, Antonella Sci Rep Article The coronavirus is caused by the infection of the SARS-CoV-2 virus: it represents a complex and new condition, considering that until the end of December 2019 this virus was totally unknown to the international scientific community. The clinical management of patients with the coronavirus disease has undergone an evolution over the months, thanks to the increasing knowledge of the virus, symptoms and efficacy of the various therapies. Currently, however, there is no specific therapy for SARS-CoV-2 virus, know also as Coronavirus disease 19, and treatment is based on the symptoms of the patient taking into account the overall clinical picture. Furthermore, the test to identify whether a patient is affected by the virus is generally performed on sputum and the result is generally available within a few hours or days. Researches previously found that the biomedical imaging analysis is able to show signs of pneumonia. For this reason in this paper, with the aim of providing a fully automatic and faster diagnosis, we design and implement a method adopting deep learning for the novel coronavirus disease detection, starting from computed tomography medical images. The proposed approach is aimed to detect whether a computed tomography medical images is related to an healthy patient, to a patient with a pulmonary disease or to a patient affected with Coronavirus disease 19. In case the patient is marked by the proposed method as affected by the Coronavirus disease 19, the areas symptomatic of the Coronavirus disease 19 infection are automatically highlighted in the computed tomography medical images. We perform an experimental analysis to empirically demonstrate the effectiveness of the proposed approach, by considering medical images belonging from different institutions, with an average time for Coronavirus disease 19 detection of approximately 8.9 s and an accuracy equal to 0.95. Nature Publishing Group UK 2023-01-10 /pmc/articles/PMC9830129/ /pubmed/36627339 http://dx.doi.org/10.1038/s41598-023-27697-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Mercaldo, Francesco Belfiore, Maria Paola Reginelli, Alfonso Brunese, Luca Santone, Antonella Coronavirus covid-19 detection by means of explainable deep learning |
title | Coronavirus covid-19 detection by means of explainable deep learning |
title_full | Coronavirus covid-19 detection by means of explainable deep learning |
title_fullStr | Coronavirus covid-19 detection by means of explainable deep learning |
title_full_unstemmed | Coronavirus covid-19 detection by means of explainable deep learning |
title_short | Coronavirus covid-19 detection by means of explainable deep learning |
title_sort | coronavirus covid-19 detection by means of explainable deep learning |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830129/ https://www.ncbi.nlm.nih.gov/pubmed/36627339 http://dx.doi.org/10.1038/s41598-023-27697-y |
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