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ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is an ultrarare thrombotic disease caused by autoantibody-induced ADAMTS13 deficiency. Open ADAMST13 conformation, induced by autoantibodies, was identified as a novel biomarker for iTTP. Determining immunoprofiles in patients with iTTP has...

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Detalles Bibliográficos
Autores principales: Sakai, Kazuya, Matsumoto, Masanori, De Waele, Laure, Dekimpe, Charlotte, Hamada, Eriko, Kubo, Masayuki, Tersteeg, Claudia, De Meyer, Simon F., Vanhoorelbeke, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830168/
https://www.ncbi.nlm.nih.gov/pubmed/36306339
http://dx.doi.org/10.1182/bloodadvances.2022008885