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ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is an ultrarare thrombotic disease caused by autoantibody-induced ADAMTS13 deficiency. Open ADAMST13 conformation, induced by autoantibodies, was identified as a novel biomarker for iTTP. Determining immunoprofiles in patients with iTTP has...
Autores principales: | Sakai, Kazuya, Matsumoto, Masanori, De Waele, Laure, Dekimpe, Charlotte, Hamada, Eriko, Kubo, Masayuki, Tersteeg, Claudia, De Meyer, Simon F., Vanhoorelbeke, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830168/ https://www.ncbi.nlm.nih.gov/pubmed/36306339 http://dx.doi.org/10.1182/bloodadvances.2022008885 |
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