Mapping transcriptional heterogeneity and metabolic networks in fatty livers at single-cell resolution

Non-alcoholic fatty liver disease is a heterogeneous disease with unclear underlying molecular mechanisms. Here, we perform single-cell RNA sequencing of hepatocytes and hepatic non-parenchymal cells to map the lipid signatures in mice with non-alcoholic fatty liver disease (NAFLD). We uncover previ...

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Detalles Bibliográficos
Autores principales: Coassolo, Laetitia, Liu, Tianyun, Jung, Yunshin, Taylor, Nikki P., Zhao, Meng, Charville, Gregory W., Nissen, Silas Boye, Yki-Jarvinen, Hannele, Altman, Russ B., Svensson, Katrin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830221/
https://www.ncbi.nlm.nih.gov/pubmed/36636354
http://dx.doi.org/10.1016/j.isci.2022.105802

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