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DNA damage repair gene mutations predict the efficacy of platinum-based chemotherapy and immunotherapy plus platinum-based chemotherapy in advanced non-small cell lung cancer: a retrospective Chinese cohort study
BACKGROUND: Platinum-based chemotherapy (PC) and immunotherapy plus platinum-based chemotherapy (IPC) remain the first-line treatment for advanced NSCLC. But only a minority patients benefit from PC, and existing biomarkers, such as PD-L1, have been shown to be defective in predicting the efficacy o...
Autores principales: | Xiao, Zhiwei, Sun, Lingling, Zheng, Yating, Chen, Hanrui, Zheng, Xinting, Luo, Jiamin, Gu, Chuying, Lin, Ruiting, Huang, Mengli, Bai, Yuezong, Chen, Zhe-Sheng, Kinslow, Connor J., Loh, Jerold, Lin, Lizhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830265/ https://www.ncbi.nlm.nih.gov/pubmed/36636408 http://dx.doi.org/10.21037/tlcr-22-746 |
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