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Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas

BACKGROUND: Patients with non-small cell lung cancer (NSCLC) harboring a ROS proto-oncogene 1 (ROS1)-rearrangement respond to treatment with ROS1 inhibitors. To distinguish these rare cases, screening with immunohistochemistry (IHC) for ROS1 protein expression has been suggested. However, the reliab...

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Detalles Bibliográficos
Autores principales: Thurfjell, Viktoria, Micke, Patrick, Yu, Hui, Krupar, Rosemarie, Svensson, Maria A., Brunnström, Hans, Lamberg, Kristina, Moens, Lotte N. J., Strell, Carina, Gulyas, Miklos, Helenius, Gisela, Yoshida, Akihiko, Goldmann, Torsten, Mattsson, Johanna Sofia Margareta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830269/
https://www.ncbi.nlm.nih.gov/pubmed/36636421
http://dx.doi.org/10.21037/tlcr-22-504